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The Patee House Hotel was used as the headquarters for the Pony Express.
Can you read the sign?
Now it is a museum ALL about St. Joseph's history. There is a dentist's chair on display there from the office of Walter Kronkite's father. He was a prominent dentist in St. Joseph some years ago. (Dorothy actually was a patient of his, and sat in that exact chair. I guess we really ARE antique!!)